Protein Purification
MilliporeSigma™ Calbiochem™ p21-Activated Kinase Inhibitor III, IPA-3
The p21-Activated Kinase Inhibitor III, IPA-3, also referenced under CAS 42521-82-4, controls the biological activity of p21-Activated Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ AG 538
A potent, cell-premeable, reversible, and competitive inhibitor of IGF-1 receptor kinase (IC50 = 400 nM).
MilliporeSigma™ Calbiochem™ PTP LYP Inhibitor
The PTP LYP Inhibitor controls the biological activity of PTP LYP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ RPA Inhibitor, TDRL-505
A cell-permeable compound that targets human Replication Protein A (RPA) and inhibits its DNA-binding activity (IC50 12.9 μM).
MilliporeSigma™ Calbiochem™ Caspase Inhibitor II
The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Gabapentin
A water soluble GABA analog that interacts with voltage-gated calcium channels in cortical neurons.
MilliporeSigma™ Calbiochem™ Glucokinase Activator III, Ro-28-1675
A cell-permeable activator of glucokinase. Exhibits in vivo glucose-lowering and insulin-releasing activity
MilliporeSigma™ Calbiochem™ KMO Inhibitor II, JM6
The KMO Inhibitor II, JM6 controls the biological activity of KMO. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphate, Sodium Salt
Important intracellular second messenger implicated in the action of nitric oxide in many cell types.
MilliporeSigma™ Calbiochem™ GCase Activator, NCGC00188758
A cell-permeable pyrazolopyrimidine-carboxamide compound that directly binds to glucocerebrosidase (GCase; Kd ∽ 9μM for NT-467 fluorescent labeled GCase) and enhances its activity and serves as a chaperone for its translocation to the lysosomal compartment in fibroblasts of patients with Gaucher disease (AC50
MilliporeSigma™ Calbiochem™ LDN-211904
LDN-211904 modulates the biological activity of EphB3 receptor tyrosine kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ MMP-3 Inhibitor II
The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ InSolution™ Sirtinol
A cell-permeable 2-hydroxy-1-napthaldehyde derivative that acts as a specific and a direct inhibitor of sirtuin class of histone deacetylase (HDAC) activity
MilliporeSigma™ Calbiochem™ InSolution™ Purmorphamine
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
MilliporeSigma™ Calbiochem™ BMX/BTK Inhibitor II, QL47
A cell-permeable, highly potent, selective, irreversible inhibitor of BTK (IC50 = 6.6 nM).